User:ElNando888/Blog/Mimic

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This entry won't develop much to a blog post. I'm just throwing ideas in the context of a discussion I'm having with Brourd about mimcs.

 

<tbody> </tbody>
1FMN stacking pattern.png Sarcin-ricin stacking pattern.png
FMN Sarcin-ricin (15 nts)

 

The top half is structurally quite similar, but the bottom differs a bit. Specifically, it is undeniable that the FMN molecule offers a much larger stacking area than the A+A platform in motif IL_85647.3

 

<tbody> </tbody>
1FMN stacking pattern.png Sarcin-ricin (reduced) stacking pattern.png
FMN Sarcin-ricin (13 nts)

 

A possible way to compensate the difference would be to use a reduced form of the loop, with an additional cWW pair, like in motif IL_49493.4