Ribosome: Difference between revisions
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<p>The <strong>ribosome</strong> is the nanomachine that | <p>The <strong>ribosome</strong> is the nanomachine that translates RNA [[base]]s from [[messenger RNA]] into [[amino acid]]s and [[protein]]s. The principle function of a ribosome is to take [[messenger RNA]] (mRNA) derived from genes (typically stored as DNA) and use them as a template or recipe to construct poly-peptides ([[protein]]s) by matching 3-base RNA triplets (codons), one at a time, to [[amino acid]]s using transfer rna (tRNA) to aid in the process.</p> | ||
<h2>Teaching about Ribosomes</h2> | <h2>Teaching about Ribosomes</h2> | ||
<ul> | <ul> | ||
<li>[http://theoncologist.alphamedpress.org/content/5/6/508.full The Molecular Perspective: The Ribosome]</li> | <li>[http://theoncologist.alphamedpress.org/content/5/6/508.full The Molecular Perspective: The Ribosome]</li> | ||
<li>[http://blogs.sciencemag.org/origins/2009/02/deconstructing-the-ribosome.html Deconstructing the Ribosome] </li> | <li>[http://blogs.sciencemag.org/origins/2009/02/deconstructing-the-ribosome.html Deconstructing the Ribosome] </li> | ||
<li>[http://en.wikipedia.org/wiki/Ribosome Ribosome - Wikipedia]</li> | |||
</ul> | |||
<h2>Labs and Puzzles for Ribosomes</h2> | |||
<ul> | |||
<li>[https://eternagame.org/web/lab/9215705/ Ribosome Pilot Challenge Warm-Up Lab]</li> | |||
<li>[https://eternagame.org/web/lab/9162726/ Ribosome Pilot Challenge Lab]</li> | |||
<li>[https://eternagame.org/web/playerpuzzles/?search=:RibosomeChallenge&sort=solved Ribosome Challenge Puzzles]</li> | |||
<li>[https://eternagame.org/web/playerpuzzles/?search=Ribosome&sort=date Ribosome Player-Puzzles]</li> | |||
</ul> | |||
<h2>Selected Forum Posts</h2> | |||
<ul> | |||
<li>[https://getsatisfaction.com/eternagame/topics/ribosome-pilot-challenge Ribosome Pilot Challenge]</li> | |||
<li>[https://getsatisfaction.com/eternagame/topics/redesigning-the-ribosome-chemical-goals Redesigning the ribosome: chemical goals]</li> | |||
<li>[https://getsatisfaction.com/eternagame/topics/ribosome-challenge-puzzles-of-the-week Ribosome Challenge Puzzles of the Week]</li> | |||
<li>[https://getsatisfaction.com/eternagame/topics/domain-structure-of-the-ribosome Domain structure of the Ribosome]</li> | |||
</ul> | |||
<h2>Puzzle Solving Resources</h2> | |||
<ul> | |||
<li>[https://eternagame.org/web/player/259016/ prestonzen] is creating another great resource for learning to solve Eterna puzzles -- YouTube video walk-throughs. His first Ribosome Challenge video, where he solves puzzle 1.7, is a very gentle introduction.</li> | |||
<li>[https://eternagame.org/web/player/215715/ Astromon]'s <a href="https://docs.google.com/presentation/d/1tryel6znJc7DF7mjojRwzVaJeK8Rm5w9s9aRFMsNeZY/edit#slide=id.g5a6ab68da6_0_0">Guide for the Ribosome labs/challenges and The Soft Constraint booster</a>.</li> | |||
<li>[https://eternagame.org/web/player/8627/ Eli]'s <a href="https://docs.google.com/document/d/1UHLuJm8Xh0td_lzWHMv-tp_7fCRCK630LBseGC7-nZY/edit#heading=h.rrdxtye6vn90">Solving ribosome challenge puzzles</a> document.</li> | |||
<li>The <a href="https://docs.google.com/presentation/d/1Q9qVUBm3l5k4lZ3hhnoObWsQhvELrfQEfslZOnWTFOs/edit#slide=id.g5d1d569447_0_0">slide presentation</a> from [https://eternagame.org/web/player/57675/ Omei]'s Eternacon presentation.</li> | |||
</ul> | |||
<h2>Puzzle Construction/Analysis Resources</h2> | |||
<ul> | |||
<li>[https://docs.google.com/document/d/1WHhQAYo1lPzII5It0gRLQKxUkY9fwmvRpVe4ouCV98g/edit?usp=sharing Ribosome Challenge Puzzle Creation] contains the scondary structure, starting sequence, IUPAC constraints and locks for the three major robosome units and their domains.</li> | |||
<li><a href="http://apollo.chemistry.gatech.edu/RibosomeGallery/E%20coli/SSU/3D%20structure%20based/index.html#E_coli.png" target="_blank">16S Diagram</a></li> | |||
<li><a href="http://apollo.chemistry.gatech.edu/RibosomeGallery/E%20coli/LSU/3D%20structure%20based/index.html#E_coli.png" target="_blank">23S Diagram</a></li> | |||
</ul> | |||
<p> </p> | |||
<ul> | |||
</ul> | </ul> |
Revision as of 03:23, 30 September 2019
The ribosome is the nanomachine that translates RNA bases from messenger RNA into amino acids and proteins. The principle function of a ribosome is to take messenger RNA (mRNA) derived from genes (typically stored as DNA) and use them as a template or recipe to construct poly-peptides (proteins) by matching 3-base RNA triplets (codons), one at a time, to amino acids using transfer rna (tRNA) to aid in the process.
Teaching about Ribosomes
Labs and Puzzles for Ribosomes
- Ribosome Pilot Challenge Warm-Up Lab
- Ribosome Pilot Challenge Lab
- Ribosome Challenge Puzzles
- Ribosome Player-Puzzles
Selected Forum Posts
- Ribosome Pilot Challenge
- Redesigning the ribosome: chemical goals
- Ribosome Challenge Puzzles of the Week
- Domain structure of the Ribosome
Puzzle Solving Resources
- prestonzen is creating another great resource for learning to solve Eterna puzzles -- YouTube video walk-throughs. His first Ribosome Challenge video, where he solves puzzle 1.7, is a very gentle introduction.
- Astromon's <a href="https://docs.google.com/presentation/d/1tryel6znJc7DF7mjojRwzVaJeK8Rm5w9s9aRFMsNeZY/edit#slide=id.g5a6ab68da6_0_0">Guide for the Ribosome labs/challenges and The Soft Constraint booster</a>.
- Eli's <a href="https://docs.google.com/document/d/1UHLuJm8Xh0td_lzWHMv-tp_7fCRCK630LBseGC7-nZY/edit#heading=h.rrdxtye6vn90">Solving ribosome challenge puzzles</a> document.
- The <a href="https://docs.google.com/presentation/d/1Q9qVUBm3l5k4lZ3hhnoObWsQhvELrfQEfslZOnWTFOs/edit#slide=id.g5d1d569447_0_0">slide presentation</a> from Omei's Eternacon presentation.
Puzzle Construction/Analysis Resources
- Ribosome Challenge Puzzle Creation contains the scondary structure, starting sequence, IUPAC constraints and locks for the three major robosome units and their domains.
- <a href="http://apollo.chemistry.gatech.edu/RibosomeGallery/E%20coli/SSU/3D%20structure%20based/index.html#E_coli.png" target="_blank">16S Diagram</a>
- <a href="http://apollo.chemistry.gatech.edu/RibosomeGallery/E%20coli/LSU/3D%20structure%20based/index.html#E_coli.png" target="_blank">23S Diagram</a>