Loop

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Revision as of 20:20, 5 May 2014 by Eli Fisker (talk | contribs) (Adding content)

A loop is a region that contains unpaired nucleotides and/or noncanonical pairs. They may be classified as hairpin loops, internal loops, bulges, multiloops, and external loops. Loops often make a positive contribution to free energy and are therefore destabilizing. The loops energies are determined by the Closing Pairs, and the mismatches. (Nando)