Base

Bases

Bases are components of nucleotides, which in turn are the building blocks of RNA and DNA. The four bases commonly enountered in RNA are adenine, guanine,cytosine, and uracil. Bases are sometimes callednitrogenous bases to emphasize the presence of nitrogen in this part of the RNA molecule.

A base differs from a nucleotide in its lack of ribose and phosphate.

Base Pairing

Main Article : Base Pairing

Bases interact with one another by hydrogen bonding and stacking. These interactions help stabilize folded RNA structures. In EteRNA, three types of base pairs are encountered: AU pairs, GC pairs, and GU pairs.

Structure

Bases are flat, with the large top and bottom surfaces interacting only weakly with water. Purine bases have a a two-ring structure, while pyrimidine bases have a smaller single-ring structure.

Abbreviations

Abbreviation	Base
A	Adenine
G	Guanine
C	Cytosine
U	Uracil
R	Adenine or Guanine (Purine Bases)
Y	Cytosine or Uracil (Pyrimidine Bases)
M	Adenine or Cytosine (Amino Bases)
K	Uracil or Guanine (Keto Bases)
N	Any base