Aptamer: Difference between revisions
From Eterna Wiki
Eli Fisker (talk | contribs) m (Adding author) |
Eli Fisker (talk | contribs) m (Adding links) |
||
| Line 24: | Line 24: | ||
<h2>Teaching about Aptamers</h2> | <h2>Teaching about Aptamers</h2> | ||
<p>[http://eternawiki.org/wiki/index.php5/User:ElNando888/Blog/Aptamers Aptamers and bonuses] by [[User:ElNando888|Nando]]</p> | <p>[http://eternawiki.org/wiki/index.php5/User:ElNando888/Blog/Aptamers Aptamers and bonuses] by [[User:ElNando888|Nando]]</p> | ||
<p>[http://eterna.cmu.edu/web/blog/?skip=5&size=5 <span>Riboswitches and science on coffee] by <span>[[User:Eli Fisker|Eli Fisker]]</span></span></p> | |||
<p><span><span>[http://www.scienceinafrica.com/biotechnology/industrial/nuts-and-bolts-genius-behind-aptamers-future-drug-delivery The nuts and bolts of the genius behind aptamers - the future for drug delivery]</span></span></p> | |||
Revision as of 12:01, 30 January 2015
An aptamer is a nucleic acid that binds a target molecule.
Comparison to Antibodies
<tbody> </tbody>|
Like antibodies, RNA aptamers can be extremely specific to a target and are capable of discriminating between closely related molecules. RNA aptamers and antibodies can be generated to bind a similarly diverse array of targets. Antibodies, however, are composed of protein and must be produced by the immune cells of a living organism. Novel aptamers can be selected quicky in vitro and amplified by PCR. |
Selection of Aptamers
<tbody> </tbody>| RNA aptamers are generated by selection. The selection process begins with a large library of random sequences and removes RNAs that do not bind the target or bind nonspecifically. The selected RNAs are isolated, reverse-transcribed, amplified, and the process is repeated. |
Teaching about Aptamers
Riboswitches and science on coffee by Eli Fisker
nuts and bolts of the genius behind aptamers - the future for drug delivery
