Player-Created Guides

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This is a list of player-created guides for EteRNA. It is by no means comprehensive.






Name Author Description
Comprehensive guide to EteRNA Eli Fisker, Brourd, Starry Guide to the guides. An introduction to the game resources and how to get well started.
EteRNA Dictionary Eli Fisker A large document listing all the terms used in the other guides with pictures.
EteRNA Toolbox Eli Fisker A list of keyboard shortcuts.


Puzzle-solving Guides (single state puzzles)


Name Author Description
Loops guide mpb21 The first guide on stabilizing loops.
General strategy guides Multiple players Players sharing general puzzle solving strategies in the forum.
Puzzle Solving Guide  (Addition) Eli Fisker A great introduction for players learning how to solve puzzles.
Loop Guide Eli Fisker Useful tricks for solving tricky loops.
Multiloop Guide Eli Fisker A visual overview of how energy in multiloops can be lowered.
Tips and Tricks Eli Fisker A compilation of useful tricks for solving unusual shapes.
Stack Guide dimension9 A table of nearest-neighbor energy terms for stacks.
Hairpin Guide mat747
A picture of successful hairpin sequences in mat747's lab designs.
Boost guide  (New slide show version) Brourd A fine guide on how to stabilize loops.
Advanced Puzzle Solving Guide Drake A hardcore guide to puzzle solving, goes at puzzle solving from an energy perspective. 
Puzzle solving guide  
Brourd A fundamental guide that will show you the basics of puzzle solving.
Beginner's to Puzzle Solving Brourd A fundamental guide that will show you the basics of puzzle solving.
Challenge Puzzles Quick Solve Guide Jennifer Pearl

A visual guide showing good and bad puzzle solving style beside each other.

Puzzle-solving Guides (switches)


Switch Puzzle Guide
Eli Fisker Collection of switch puzzle guides, walkthroughs and solving methods.
Switch Training Series Nando Fantastic walkthrough giving the reasoning behind solving switches.
How to solve a switch
JR Great walkthrough on how to solve a switch puzzle.
Hand and Finger Walkthrough Meechl Visual walhthrough on how to solve a switch puzzle and get ready for lab. 
A TRIPLE SWITCH WALKTHROUGH for EteRNAddicts everywhere Jieux Awesome guide for dealing with 3 state switch puzzles.


Lab Guides


Name Author Description
Lab Guide Eli Fisker Strategies for making successful designs in lab.
Lab Guide for new players Eli Fisker More strategies for making successful designs in lab.
Lab Guide mpb21 Strategies for making successful designs in lab.
A guide to using Vienna RNA fold Eli Fisker A guide to using Vienna - for assessing potential Lab designs.
GC Pairs in Lab ccccc Why you don't want to make Christmas trees in lab.
Mat's lab design strategy Mat747 Strategies for good lab designing.
Quick guide to the lab Eli Fisker Quick introduction to the lab tools.
Ways to deal with voting in huge labs  Eli Fisker Lab voting methods.
Ways to deal with designing in huge labs Eli Fisker Methods for improved lab designing.
Switch Lab Guide Eli Fisker Collection of info on switches and advice for the switch lab designing.
General lab info and lab tech details  Eli Fisker Collection of info from chat, forum, devs etc. relevant to labs and lab designing.
CSE using LabDataMiner for Lab "Late Bulge" JandersonLee A demonstration of how to use the LabDataMiner for lab designing.
CSE for Reversed G-C Multibranch Loop Closing Base Pairs JandersonLee A demonstration of how to use the LabDataMiner for lab designing in designs with multiloops.
Reading the lab results - Intro to SHAPE data Eli Fisker Intro on how to read lab results and SHAPE data.
Lab Manual - The Eterna History Tour Eli Fisker Learn how to do lab work. This lab guide is connected to the ongoing lab project for lab introduction.
MS2 - Thoughts about the lab data Eli Fisker Mixture of analysis, chat discussions on the lab and highlighting areas of interest for designing and analysis. 
Different types of switches Eli Fisker Boiled down Switch lab Guide. Intro to switch tendencies and what has worked for them so far. 
Switch Lab Intro Eli Fisker Quick intro to main tendencies for working lab switches.
MS2 Lab Intro Eli Fisker Introduction on how to start solving a switch lab puzzle in an MS2 lab.
MicroRNA Intro Eli Fisker Introduction to microRNA, Eterna Medicine and the Feynman challenge.
Doing Math with RNA Eli Fisker Simple approach for doing math with RNA.
A Tutorial for A/B Ramp-up puzzles Omei, Eli Fisker Introduction to puzzles and lab for the A/B switch labs.
Logic Gates Eli Fisker| Pointers for the logic gates lab.


See also

Puzzle Walkthroughs

Puzzle Maker

Network Viewer Guide

Teaching and tutorial puzzles

Personal tools
Main page
Introduction to the Game